786 research outputs found

    Evidence for an active fault below the northwestern Alpine foreland of Switzerland

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    This study is devoted to the analysis of a prominent concentration of earthquakes whose epicenters delineate an active 20-30 km long N—S trending tectonic feature near the town of Fribourg, in the Molasse Basin of western Switzerland. This feature coincides with the possible southward continuation of the NNE—SSW trending Rhine Graben located approximately 80 km further north. In addition these epicenters are located in the vicinity of the Fribourg Syncline and the Alterswil Culmination, whose structural axes are oriented N—S in this area, instead of being aligned with the predominant regional NE—SW structural trend. Most of the earthquakes belong to one of three series of events that occurred over a time span of 2-4 months in 1987, 1995 and 1999. They include four events with magnitudes between 3 and 4 and one with a magnitude of 4.3. Focal depths, constrained by modelling sPMP-PMP traveltime differences with synthetic seismograms, are around 2 km, which places these events in the sedimentary cover. Fault plane solutions correspond to almost pure strike-slip mechanisms with nearly N—S and E—W oriented nodal planes. High-precision relative locations of individual events within the different earthquake clusters as well as of the relative locations of the clusters to each other show that these earthquakes are associated with left lateral motion along a N—S trending fault system. Deep reaching large scale flower structures in the Mesozoic and Tertiary overburden are observed on interpreted seismic profiles, close to the hypocenters. The unusual N—S trend of the Fribourg Syncline can be attributed to movements along these faults during Oligocene and Miocene times. Also magnetic data support the assumption of a N—S striking fault system in the Fribourg area, possibly related to a Permo-Carboniferous trough. Though the direct link between the fault traces in the overburden and the active fault system at depth could not be established in this study, their similar deformational style and their vicinity suggest that they are related. The total length of the inferred fault carries the potential of a magnitude 6 earthquake and thus constitutes a significant source of seismic hazar

    Exploring break-points and interaction effects among predictors of the international digital divide

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    Cataloged from PDF version of article.The deepening of the digital divide between countries has prompted international organizations and governments to work together toward reducing the problem over the next 15 years. However, such efforts will likely succeed only if they are based on a firm grasp of the divide's underlying causes. In this paper we report the results of a comprehensive analysis of the determinants of the international digital divide. Our results confirm many findings of past research, but also extend existing knowledge in important ways. By employing Multivariate Adaptive Regression Splines (MARS), we discover non-linearities and interaction effects among the predictors. We then articulate significant policy implications based upon these findings

    A comprehensive approach for correcting voxel‐wise b‐value errors in diffusion MRI

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    Purpose In diffusion MRI, the actual b‐value played out on the scanner may deviate from the nominal value due to magnetic field imperfections. A simple image‐based correction method for this problem is presented. Methods The apparent diffusion constant (ADC) of a water phantom was measured voxel‐wise along 64 diffusion directions at b = 1000 s/mm2. The true diffusion constant of water was estimated, considering the phantom temperature. A voxel‐wise correction factor, providing an effective b‐value including any magnetic field deviations, was determined for each diffusion direction by relating the measured ADC to the true diffusion constant. To test the method, the measured b‐value map was used to calculate the corrected voxel‐wise ADC for additionally acquired diffusion data sets on the same water phantom and data sets acquired on a small water phantom at three different positions. Diffusion tensor was estimated by applying the measured b‐value map to phantom and in vivo data sets. Results The b‐value‐corrected ADC maps of the phantom showed the expected spatial uniformity as well as a marked improvement in consistency across diffusion directions. The b‐value correction for the brain data resulted in a 5.8% and 5.5% decrease in mean diffusivity and angular differences of the primary diffusion direction of 2.71° and 0.73° inside gray and white matter, respectively. Conclusion The actual b‐value deviates significantly from its nominal setting, leading to a spatially variable error in the common diffusion outcome measures. The suggested method measures and corrects these artifacts

    A comparative analysis of cultural value orientations of Polish and Turkish employees:implications for international human resource management

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    This study empirically compares and contrasts the cultural value orientations of employees from Poland and Turkey by testing the compatibility of their values in three stages through seven cultural dimensions. The first phase of the study deals with the assessment of inter-country cultural value differences; the second phase investigates the intra-country cultural dynamics between selected demographic groups; and the third phase examines the inter-country cultural differences among the selected demographic groups of employees. The research has been conducted adopting the Maznevski, DiStephano, and Nason's (1995) version of cultural perspectives questionnaire with a sample of 744 (548 Polish and 196 Turkish) respondents. The results show significant cultural differences between Poland and Turkey, a presence of cultural dynamics among certain demographic groups within the country, and a mixture of convergence and divergence in the value systems of certain demographic groups both within and between the two nation(s). The research findings convey important messages to international human resource strategists in order for them to employ an effective and rational employment policy and business negotiation approach(es) to effectively operate in these countries. It also highlights that diversity of cultural values not only requires viewing each of them through cultural dimensions at a macro-level with a cross-country reference, but also requires monitoring their dynamics at the micro-level with reference to controlled demographic groups

    Inflammation causes mood changes through alterations in subgenual cingulate activity and mesolimbic connectivity

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    BACKGROUND: Inflammatory cytokines are implicated in the pathophysiology of depression. In rodents, systemically administered inflammatory cytokines induce depression-like behavior. Similarly in humans, therapeutic interferon-alpha induces clinical depression in a third of patients. Conversely, patients with depression also show elevated pro-inflammatory cytokines. OBJECTIVES: To determine the neural mechanisms underlying inflammation-associated mood change and modulatory effects on circuits involved in mood homeostasis and affective processing. METHODS: In a double-blind, randomized crossover study, 16 healthy male volunteers received typhoid vaccination or saline (placebo) injection in two experimental sessions. Mood questionnaires were completed at baseline and at 2 and 3 hours. Two hours after injection, participants performed an implicit emotional face perception task during functional magnetic resonance imaging. Analyses focused on neurobiological correlates of inflammation-associated mood change and affective processing within regions responsive to emotional expressions and implicated in the etiology of depression. RESULTS: Typhoid but not placebo injection produced an inflammatory response indexed by increased circulating interleukin-6 and significant mood reduction at 3 hours. Inflammation-associated mood deterioration correlated with enhanced activity within subgenual anterior cingulate cortex (sACC) (a region implicated in the etiology of depression) during emotional face processing. Furthermore, inflammation-associated mood change reduced connectivity of sACC to amygdala, medial prefrontal cortex, nucleus accumbens, and superior temporal sulcus, which was modulated by peripheral interleukin-6. CONCLUSIONS: Inflammation-associated mood deterioration is reflected in changes in sACC activity and functional connectivity during evoked responses to emotional stimuli. Peripheral cytokine

    Optimized EPI for fMRI studies of the orbitofrontal cortex: compensation of susceptibility-induced gradients in the readout direction

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    Object Most functional magnetic resonance imaging (fMRI) studies record the blood oxygen leveldependent (BOLD) signal using gradient-echo echo-planar imaging (GE EPI). EPI can suffer from substantial BOLD sensitivity loss caused by magnetic field inhomogeneities. Here, BOLD sensitivity losses due to susceptibility- induced gradients in the readout (RO) direction are characterized and a compensation approach is developed

    Measuring the international digital divide: an application of Kohonen self-organising maps

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    With the help of a Kohonen self-organising algorithm, this paper presents a mapping and analysis of the global digital divide along with its main drivers. Several broad groups and subgroups are identified, consisting of countries that are similar in their digital development and in a number of other attributes. We find that the digital divide seems to occur synchronously with divisions in income, social, demographic and infrastructure measures. By examining a large dataset of 160 countries over a short period of three years, we find evidence of both convergence and divergence among the countries over time. We expect these findings to inform the ongoing debate on drivers of the International Digital Divide (IDD). In addition, this paper provides a novel visualisation of the digital divide and its predictors on a two-dimensional grid. Extensions of this work, with the availability of more years of data, could investigate the potential convergence of countries to particular patterns of digital development. © 2007 Inderscience Enterprises Ltd
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